Podcast: MDS PODCAST: Defining Parkinson's disease

MDS Podcast MDCP Research Article of the Year: Are hyposmia and REM sleep behavior disorder reliable indicators of Lewy body pathology?

There is an important role for cost-effective clinical biomarkers in the diagnosis of Parkinson’s disease. Dr. Eduardo de Pablo-Fernández and Dr. Cecilia Tremblay discuss how accurate hyposmia and REM sleep behavior disorder can predict Lewy pathology in a non-selected population using data from the Arizona clinicopathological study on Aging and Neurodegeneration. Read the article.

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MDS Podcast MDCP Review of the Year: Why should subacute sclerosing panencephalitis be on our radar?

This year’s MDCP Review Article of the Year covers the spectrum of movement disorders associated with subacute sclerosing panencephalitis (SSPE). Dr. Sarah Camargos interviews Dr. Charulata Sankhla on her team’s findings and why she believes movement disorder specialists should be aware of this measle-associated complication. Read the article.

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MDS Podcast Presidential Lecture Awardee: A career observing the brain in action | Congress 2025

Dr. Jon Stoessl looks back on his distinguished career in neuroimaging, highlighting the discoveries that have advanced our understanding of Parkinson’s disease and related conditions. In this conversation, he reflects on the evolution of imaging technologies, the challenges of interpreting complex data, and the lessons learned throughout his journey. His recognition with the David Marsden…

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MDS Podcast Presidential Lecture Awardee: Holistic conceptualization of patients with chronic illness | Congress 2025

Prof. Mark Edwards, the awardee for the 2025 Stanley Fahn Lecture Award, discusses his work and interest in the neurology-psychiatry continuum as it relates to the care of patients with chronic neurological diseases, including functional neurological disorders.

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MDS Podcast Decoding epilepsy dyskinesia syndrome: Clinical clues and genotypic spectrum

In this episode, we dive into the world of epilepsy dyskinesia syndrome (EDS) with our guest, Dr. Darius Ebrahimi-Fakhari. Listen as he unpacks the findings from one of the largest multinational studies to date, involving over 600 patients across 25 countries. Read the article.

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MDS Podcast Hot Topic: Normal pressure hydrocephalus – Assessments for intervention, outcomes, and future directions

In the third and final episode of the normal pressure hydrocephalus (NPH) Hot Topic series, Dr. Sara Schaefer speaks with Dr. Joachim Krauss about the assessment of patients with NPH for neurosurgical intervention, outcomes data, and his vision for the future of NPH research and clinical care.

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MDS Podcast Hot Topic: Normal pressure hydrocephalus – Pathophysiology and controversies

In this second episode of the Hot Topic series on normal pressure hydrocephalus, Dr. Sara Schaefer discusses with Dr. Alfonso Fasano the pathophysiological theories behind NPH, co-pathology in this population, and controversies surrounding the disease.

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MDS Podcast Hot Topic: Normal pressure hydrocephalus – Clinical aspects and differential diagnosis

In this first episode of the Hot Topic series on normal pressure hydrocephalus, Dr. Sara Schaefer discusses with Dr. Mats Tullberg the symptoms of NPH, examination techniques and pearls, imaging findings, and the differential diagnosis.

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MDS Podcast The cholinergic contribution to freezing of gait in Parkinson’s disease

In this episode, host Dr. Michele Matarazzo interviews Dr. Nicolaas Bohnen about his team’s recent study using FEOBV PET to investigate cholinergic deficits in Parkinson’s disease patients with dopa-unresponsive freezing of gait (FOG). The results reveal a distinct pattern of cortical cholinergic denervation that may underlie this challenging and poorly treatable symptom. Dr. Bohnen discusses…

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MDS Podcast The longest prospective study of pallidal DBS for isolated dystonia

Dr. Mitra Afshari interviews Drs. Patricia Krause and Andrea Kühn on the results of a 10-year prospective follow-up study of a multicenter trial of GPI-DBS in isolated generalized and segmental dystonia. Together they discuss motor, non-motor, and safety outcomes, as well as the strong and stable long-term improvements in dystonia from pallidal DBS. Further, they…

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