Podcast: MDS PODCAST: Defining Parkinson's disease

MDS Podcast Differential diagnosis of myoclonus

Prof. Marina de Koning-Tijssen interviews Dr. Christos Ganos on the differential diagnosis of myoclonus. Dr. Ganos explains how he distinguishes between jerky movements based on clinical history and examination, and discusses the differential diagnosis across various parts of the body.

Read More

MDS Podcast Intraventricular infusion of anaerobic dopamine

Dr. Hugo Morales Briceno interviews Prof. David Devos from the University of Lille, France, about the results of the phase 1/2 clinical trial using intracerebroventricular anaerobic dopamine in Parkinson’s disease with L-dopa-related complications. Read the article.

Read More

MDS Podcast Electrophysiology with a focus on cortical myoclonus

Prof. Marina de Koning-Tijssen interviews Professors Anna Latorre and Shabbir Merchant on the topic of electrophysiology, with a focus on cortical myoclonus. Together they discuss the potential applications of electrophysiology for myoclonus in clinical practice. They also explore the complex interface between cortical myoclonus and epilepsy.

Read More

MDS Podcast What can the locus coeruleus tell us about cognition in Lewy body disorders?

Dr. Michele Matarazzo interviews Prof. Irena Rektorová about her recent study on early changes in the locus coeruleus in mild cognitive impairment with Lewy bodies. Using neuromelanin-sensitive MRI, the study reveals selective vulnerability of the caudal locus coeruleus and its association with specific cognitive and other nonmotor features. The conversation explores the implications for early…

Read More

MDS Podcast Myoclonus new classification & treatment

Prof. Marina de Koning-Tijssen interviews Prof. John Caviness on the topic of myoclonus, focusing on its new classification and treatment. They discuss the long-awaited recently published classification of myoclonus and explore the latest treatment options.

Read More

MDS Podcast Celebrating the Parkinson’s community

On this special World Parkinson’s Day episode, Dr. Michele Matarazzo is joined by John Dean—speech-language pathologist and Chair of the MDS Allied Health Professionals Group—to explore the essential roles of care partners, allied health professionals, and the broader Parkinson’s community. From physiotherapists to family members, we shine a light on the many people who support…

Read More

MDS Podcast Gender differences in DBS decision making

Dr. Sara Schaefer discusses with Dr. Michelle Fullard the similarities and differences in how men and women with Parkinson’s disease approach the decision of whether or not to undergo deep brain stimulation. Read the article.

Read More

MDS Podcast GLP-1 agonists in Parkinson’s disease: New evidence, new questions?

In this episode, Dr. Michele Matarazzo interviews Prof. Tom Foltynie about the recently published phase 3 clinical trial of exenatide as a disease-modifying therapy for Parkinson’s disease in The Lancet. While the findings were disappointing, ongoing post-hoc analyses aim to understand the discrepancy with previous phase 2 results and explore how they might shape the…

Read More

MDS Podcast Mitochondrial DNA copy number: A potential biomarker for Parkinson’s disease progression

Prof. Sarah Camargos interviews Prof. Sun Ju Chung about his recent paper in the Movement Disorders Journal investigating diagnostic and prognostic capabilities of measuring blood mitochondrial DNA copy number (mtDNA-CN) for Parkinson’s disease. Journal CME is available until March 3, 2026 Read the article.

Read More

MDS Podcast tDCS for Tourette syndrome

Dr. Sara Schaefer and Dr. Davide Martino discuss his recent paper exploring the use of transcranial direct current stimulation over the supplementary motor area for the suppression of tics in patients with Tourette Syndrome. Read the article.

Read More