Podcast: MDS PODCAST: Defining Parkinson's disease

MDS Podcast MDJ Research Article of the Year: Microglial activation in isolated REM sleep behavior disorder

Dr. Michele Matarazzo interviews Dr. Victor Hvingelby, the recipient of this year’s MDJ Research Article of the Year award. Together they discuss the use of PET tracers to assess microglial activation in isolated REM sleep behavior disorder and how these tools can better define prodromal Parkinson’s disease.

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MDS Podcast Highlights for dystonia • 2025 MDS Congress

Prof. Susanne Schneider discusses all things dystonia. Listen as she reviews the revised MDS definition and classification system for dystonia, updates for neurodegeneration with brain iron accumulation, and the exciting future of genetic therapies.

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MDS Podcast Breaking down functional movement disorders • 2025 MDS Congress

Functional movement disorders (FMDs) are the most common subgroup of functional neurological disorders. Prof. Selma Aybek breaks down current trends for FMDs, controversies, and treatment preferences, including implementing an interdisciplinary team.

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MDS Podcast Current microbiome research for Parkinson’s disease • 2025 MDS Congress

Prof. Paul Wilmes breaks down his #mdscongress talk discussing the recent studies on the influences of the gut microbiome on PD. He also dives into future goals and what interventions may be beneficial for PD.

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MDS Podcast Current status of functional neurosurgery • 2025 MDS Congress

There have been major breakthroughs in functional neurosurgery. Prof. Jill Ostrem breaks down the latest updates in the field, specifically surrounding adaptive DBS.

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MDS Podcast What’s new for MSA? • 2025 MDS Congress

Prof. Alessandra Fanciulli discusses how the MDS criteria for the diagnosis of MSA has made an impact on the field, the status of biomarker research, and optimal targets for disease-modifying trials for MSA.

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MDS Podcast What’s next? Updates in functional neuroimaging • 2025 MDS Congress

Developments in neuroimaging have grown a lot over the years. Dr. Thilo van Eimeren discusses biomarker development, both in tau and alpha synuclein, current research, and his hope for future successes.

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MDS Podcast Disease modification and Parkinson’s disease: Clinical trial design and population selection • 2025 MDS Congress

There have been nearly 30 years of disease modifying trials for PD, but little success. Prof. Tanya Simuni breaks down clinical trial design for a heterogenous disease like PD and discusses the future goals and importance of a biological definition.

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MDS Podcast Current genetic landscape for movement disorders • 2025 MDS Congress

The field of genetics often moves quickly, making it a challenge to stay informed. Dr. Gerard Saranza breaks down the current landscape, new discoveries and technologies, and what changes we can expect in the upcoming years.

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