ALS

Neurology® Podcast Characteristics and Motivations of People With ALS Who Pursue Medical Aid in Dying – Part 2

In the second part of this two-part series, Dr. Robert Holloway talks with Dr. Carolyn Rennels about legal and ethical considerations, the importance of interdisciplinary support, and the emotional impact on clinicians.  Read the related…

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Neurology® Podcast Characteristics and Motivations of People With ALS Who Pursue Medical Aid in Dying – Part 1

In the first part of this two-part series, Dr. Robert Holloway talks with Dr. Carolyn Rennels about the background of the study, the definition and practice of MAID, and the main reasons that lead ALS patients to consider it. Read the related article…

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Neurology® Podcast Implications for Diagnostic Criteria for Primary Lateral Sclerosis

Dr. Jeff Ratliff talks with Drs. Michael A. Van Es and Eva de Boer about the current diagnostic criteria for PLS, the role of genetic testing, and the clinical implications for patient management.  Read the related article in .  Read the…

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Neurology® Podcast Revolutionizing ALS Treatment: The Tofersen Breakthrough

Dr. Gordon Smith talks with Dr. Timothy Miller about compelling patient stories and clinical data that highlight the potential for recovery in ALS patients, emphasizing the importance of early intervention and understanding the disease mechanisms….

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Neurology® Podcast End-of-Life Health Care Service Use and Cost

Dr. Gordon Smith talks with Dr. Whitley Aamodt about end-of-life care for patients with neurodegenerative diseases, focusing on healthcare utilization, hospice enrollment, and the importance of early conversations about care preferences. Read the…

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Neurology® Podcast Incorporating Genetic Testing Into the Care of Patients with ALS/FTD

Dr. Gordon Smith talks with Laynie Dratch about integrating genetic testing into patient care for persons with Amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD) spectrum disorders. Read the related article in . …

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Neurology® Podcast September 2023 Neurology Recall: Topics in ALS

The September 2023 Neurology Recall showcases five dynamic interviews about ALS. The episode begins with a discussion about the strategic plan for ALS from the NINDS with . This episode features conversations with on simulation based interim analysis…

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Neurology® Podcast A Neurologist’s Experience as a Patient with ALS

Dr. Gordon Smith talks with Dr. Ajay Sampat about his journey of being a neurologist and getting diagnosed with ALS at 36. Visit for additional podcasts and associated article links.  

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Neurology® Podcast Simulation-Based Planning of ALS Trials

Dr. Gordon Smith talks with Drs. Ruben P.A. van Eijk and Jordi van Unnik about the planning of interim analyses for clinical trials in ALS to maximize patient safety and minimize exposure to ineffective or harmful drugs. Read the related article in…

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Neurology® Podcast FDA Approved Therapy for SOD1 Associated ALS

Dr. Gordon Smith talks with Dr. Suma Babu about a newly approved treatment for ALS that is associated with a mutation in the superoxide dismutase 1 (SOD1) gene. Read the related article on the .  Disclosures can be found at 

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