Podcast: MDS PODCAST: Defining Parkinson's disease

MDS Podcast Getting involved in the MDS: a fruitful relationship

In this episode, Michele Matarazzo highlights the relevance of our society for the field and its members, with special guest Njideka Okubadejo.

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MDS Podcast Inflammation is an early feature of Parkinson’s disease

Dr. Michele Matarazzo interviews Dr. Talene Yacoubian on an article recently published on the Movement disorders journal that reveals increased inflammatory markers in recently diagnosed patients with Parkinson’s disease without medication, suggesting the important role of inflammation from the early stages of the disease. Furthermore, inflammatory biomarkers are related to cognition. Journal CME is available…

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MDS Podcast Diagnosis of Late-Onset Wilson’s Disease

Dr. Christelle Nilles talks with Dr. Hugo Morales Briceno about the clinical presentations of Wilson’s disease patients with onset after 40 years and the challenges of diagnosing patients with atypical neurological manifestations. Read the article.

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MDS Podcast Deep brain stimulation in Parkinson’s disease with cognitive impairment: real-world evidence

Deep brain stimulation (DBS) has long been considered a risky procedure for people with Parkinson’s disease and cognitive impairment. In this interview, Dr. Miocinovic presents real-world data, showing that DBS might be safe and useful in carefully selected patients with moderate cognitive impairment. Read the article.

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MDS Podcast History of Movement Disorders: The Finding of Alpha-Synuclein and Lewy Bodies

In this History of Movement Disorders Special Episode, Prof. Tiago Outeiro interviews Prof. Maria Grazia Spillantini about integral work involved in discovering the role alpha-synuclein plays in the development of Lewy bodies. She discusses where the field is now and what questions young researchers should start asking.

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MDS Podcast Hot topic: The gut microbiome in Parkinson’s

In this special Hot Topics episode, Dr. Filip Scheperjans discusses what we know and what we don’t yet know about the gut microbiome in Parkinson’s disease, theories of influencing pathways within the gut-brain axis, and future directions for exploring and altering the gut microbiome in this patient population to impact disease.

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MDS Podcast Pathological Validation of 2022 MSA Criteria

Sara Schaefer discusses with Dr. Eduardo de Pablo-Fernandez his recent paper in Movement Disorders providing retrospective pathological validation of the 2022 MDS MSA Criteria using specimens from the Queens Square Brain Bank. Read the article.

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MDS Podcast Walking through the falls: understanding gait with wearable sensors in Parkinson’s disease

In this paper, Dr. Vrustangkumar Shah and colleagues evaluated gait in patients with Parkinson’s disease in the lab and in real life, with and without levodopa through wearable sensors. Some measures are able to discriminate fallers from non-fallers in PD. Read the article.

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