Podcast: MDS PODCAST: Defining Parkinson's disease

MDS Podcast Local fields potentials can help DBS programming in Parkinson’s disease in clinical practice

Dr. Michele Matarazzo interviews Prof. Andrea Kühn on her recently published article showing the potential of local fields potentials to help the programming of deep brain stimulation in patients with Parkinson’s disease. Read the article

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MDS Podcast Deep brain stimulation for GBA-related Parkinson’s disease: is it a reasonable option?

In this special issue Dr. Avenali and Prof. Valente share the results on a large cohort study investigating the results and risks of deep brain stimulation in people with Parkinson’s disease carrying a GBA mutation. Read the article

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MDS Podcast Family history and genetic Alzheimer’s risk and ties to Parkinson’s disease

Dr. Sara Schaefer discusses with Prof. Xiang Gao and Xinming Xu on their study utilizing the UK biobank to explore the risk of Parkinson’s disease as it relates to family history of Alzheimer’s disease (AD) or dementia and to the polygenic risk score for AD. They further explore the common pathophysiological underpinnings for protein aggregation…

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MDS Podcast Unravelling the progression of tremor in Parkinson’s disease

Dr. Pasquini discusses the findings of his collaborative study that has helped to understand the progression of rest postural and kinetic tremor in Parkinson’s disease. Read the article

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MDS Podcast Using EEG to Identify Parkinson’s Subtypes

Dr. Sara Schaefer discusses with Prof. Marc Vérin and Prof. Mahmoud Hassan their recent paper in Movement Disorders Journal on the use of Resting-State High-Density EEG to neurophysiologically stratify Parkinson’s patients into subtypes in an effort to predict cognitive and motor progression, properly evaluate for invasive therapies, and inform future clinical research. Read the article

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MDS Podcast Hot Topic: Tissue-based biomarkers in Parkinson’s disease

For this Hot Topics episode, Dr. Eduardo Fernandez sits down with Dr. Thomas Beach to discuss the advances and challenges ahead in tissue biomarkers for Parkinson’s disease, including colon, salivary gland and skin biopsies.

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MDS Podcast Expanded and Independent Spanish Validation of the MDS Non-Motor Rating Scale

Dr. Esther Cubo joins Dr. Sarah Lidstone and the MDS Podcast to discuss her recent work on the Spanish validation of the MDS Non-Motor Rating Scale. Together to go over the reasoning for this study, the extensive process of validating this scale and what benefits it will provide to Spanish speaking populations. Read the article…

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MDS Podcast Hot topic: GP2 and underrepresented populations

The Global Parkinson’s Genetics Program (GP2) is a project designed to understand the architecture of Parkinson’s disease (PD). Dr. Sarah Camargos sits down with Dr. Andrew Singleton to discuss GP2 and its initiative to increase our global understanding of PD and in doing so, better understand the genetic landscape of underrepresented populations.

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MDS Podcast Task-specific brain oscillatory activity in laryngeal dystonia

Laryngeal dystonia (LD) is a rare disorder affecting the vocal cords. Dr. Sarah Camargos sits down with Prof. Kristina Simonyan while she breaks down the methodology and findings of her comprehensive study investigating the temporal-spatial signature of LD. Read the article

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MDS Podcast MDCP Review Article of the Year: Alpha-Synuclein Seed Amplification Assays in CSF

Dr. Sara Schaefer speaks with Dr. Beatrice Heim, author of the MDCP Review Article of the Year 2023, about alpha-synuclein seed amplification assays of the CSF and their use in the diagnosis of synucleinopathies. Read the article

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