1) Motor cortex inhibition and 2) Topic of the month: Neurotoxins. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. John Mytinger interviews Dr. Don Gilbert about his paper on motor cortex inhibition. In the next segment, Dr. Stacey Clardy is reading our e-Pearl of the week about ictal asystole. In the next part of the podcast Dr. Beau Bruce interviews Dr. Jonathan Rutchik about neurolgic effects of organic solvents for our Lesson of the Week. Next week, we will discuss ciguatera poisoning. The participants had nothing to disclose except Drs. Gilbert, Clardy and Bruce.Dr. Gilbert has received honoraria from the Tourette Syndrome Association/ Centers for Disease Control, the Movement Disorder Society, the American Academy of Neurology, and the American Academy of Pediatrics; serves on the medical advisory board for the Tourette Syndrome Association; writes board review questions for PREP SA (American Academy of Pediatrics); has received research support from the NIH [NIMH R01 MH078160, NIMH R01 MH08185, and NINDS NS056276], and from Cincinnati Children’s Hospital Research Foundation, the University of Cincinnati, and the Tourette Syndrome Association.Dr. Clardy serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Bruce has received grant funding from the AAN/AANF Practice Research Fellowship and is funded by NIH grants UL1-RR025008 and KL2-RR025009.