The August 2022 replay of past episodes showcases recent interviews in the realm of Parkinson disease (PD), with topics ranging from initial clinical management to more advanced methodologies to optimize treatment. This episode features conversations with Dr. Anthony Lang, Dr. Meredith Bock, and Dr. Jan Rusz on dopamine-based therapies in early PD, factors associated with quality of life in PD, and new research on speech impairment subtypes in PD, respectively. The episode concludes with Dr. Michael Fox discussing brain networks and their role in cognitive decline after DBS surgery.