This Podcast for the Neurology Journal begins with Dr. John H. Noseworthy, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Beau Bruce interview Dr. Brian G. Weinshenker, Professor of Neurology from the Mayo Clinic about his team’s paper on NMO-IgG predicts outcome of recurrent optic neuritis. The podcast concludes with Dr. Ted Burns interviewing Dr. Robert J. Joynt, Section Editor for the Changes People Comments Section with one to be published in this issue. The participants had nothing to disclose.