Poliovirus-infected macrophages in thymus and part two on evidence-based medicine. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Ted Burns interviews Dr. Renato Bernasconi about his paper on myasthenia gravis. In the next segment, Dr. Ryan Overman is reading our e-Pearl of the week about a mimic of hemicranias continua. In the next part of the podcast Dr. Michael Benatar interviews Dr. Gary Gronseth for part two on evidence-based medicine for our Lesson of the Week. The participants had nothing to disclose except Drs. Burns and Gronseth.Dr. Burns receives a stipend as Podcast Editor for Neurology®, and performs EMG studies in his neuromuscular practice (30% effort).Dr. Gronseth serves as an editorial advisory board member of Neurology Now; serves on a speakers bureau for Boehringer Ingelheim; and receives honoraria from Boehringer Ingelheim and the American Academy of Neurology.