1) Orthostatic intolerance and 2) Topic of the month: Evaluation of polyneuropathy. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Ted Burns with Dr. Paola Sandroni about her paper on orthostatic intolerance. Dr. Jennifer Fugate is reading our e-Pearl of the week about bright tongue sign. In the next part of the podcast Dr. Ted Burns interviews Dr. Vera Bril about symptomatic treatment of painful diabetic neuropathy. The participants had nothing to disclose except Drs. Burns, Sandroni, Fugate and Bril.Dr. Burns serves as Podcast Editor for Neurology®; performs EMG studies in his neuromuscular practice (35% effort); and has received research support for consulting activities with CSL Behring and Alexion Pharmaceuticals.Dr. Sandroni receives research funding from the NIH.Dr. Fugate serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Bril received speakers’ fees from Pfizer Inc and for a talk last year for European Federation of Neurological Societies and received research funding from Talecris Biotherapeutics, Inc..