MDS PODCAST: Defining Parkinson’s disease

Stay up to date on novel, clinically-relevant research findings in Parkinson's disease and other movement disorders.

Stay up to date on novel, clinically-relevant research findings in Parkinson’s disease and other movement disorders.


All Episodes

MDS Podcast The cholinergic contribution to freezing of gait in Parkinson’s disease

In this episode, host Dr. Michele Matarazzo interviews Dr. Nicolaas Bohnen about his team’s recent study using FEOBV PET to investigate cholinergic deficits in Parkinson’s disease patients with dopa-unresponsive...

MDS Podcast The longest prospective study of pallidal DBS for isolated dystonia

Dr. Mitra Afshari interviews Drs. Patricia Krause and Andrea Kühn on the results of a 10-year prospective follow-up study of a multicenter trial of GPI-DBS in isolated generalized and...

MDS Podcast Neurotrophic factors to restore dopaminergic terminals in Parkinson’s disease: A viral vector-delivered genetic therapy

Could gene therapy with neurotrophic factors help restore dopaminergic terminals in Parkinson’s disease? Dr. Michele Matarazzo speaks with Dr. Amber Van Laar about her team’s Phase 1b trial of AAV2–GDNF...

MDS Podcast Do social workers play a role in preoperative evaluation for DBS?

Nicole Duff and Dr. Amanda Currie discuss the potential role of the social worker in deep brain stimulation (DBS) and the work of Dr. Currie’s team in creating a...

MDS Podcast Surprise neuropathological findings in LRRK2 mutation carriers

Mutations in LRRK2 are a common cause of familial and sporadic Parkinson’s. Though clinical features resemble typical PD, about half of cases lack Lewy pathology. Doctors Hiroaki Sekiya and...

MDS Podcast Artificial intelligence in the diagnostic approach of chronic ataxias

Dr. Hugo Morales interviews Drs. Malco Rossi and Lucas Alessandro about their work on an AI-powered virtual assistant designed to aid in the diagnosis of chronic ataxias. They discuss...

MDS Podcast Prime editing – A future therapy for cortical myoclonus?

Prof. Marina de Koning-Tijssen interviews Prof. Sabine Fuchs on the potential of prime editing as a future therapy for cortical myoclonus. This exciting new development holds promise for the...

MDS Podcast History of Movement Disorders: The story of MPTP and parkinsonism

In this episode, Prof. Tiago Outeiro interviews Prof. William Langston on the intriguing history of drug addicts manifesting parkinsonism in the 1980s, and how MPTP became a tool compound...

MDS Podcast Myoclonus dystonia: Motor & non-motor symptoms and the effect of DBS

Prof. Marina de Koning-Tijssen interviews Prof. Kathryn Peall about her expertise on a topic that lies at the heart of her work: Myoclonus dystonia. We’ll hear her insights on...